AMSTAR 2: A Critical Appraisal Tool for Systematic Reviews that Include Randomised and/or Non-Randomised Studies of Healthcare Interventions

Shea B. J., Reeves B. C., Wells G., Thuku M., Hamel C., Moran J. et al. (2017). AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. BMJ, 358. https://doi.org/10.1136/bmj.j4008

Description

This critical appraisal tool is designed for systematic reviews that include randomized, non-randomized studies, or both.

Steps for Using Method/Tool

The tool guides users through a series of questions (yes/partial yes/no) that results in an overall rating of high, moderate, low or critically low quality.

Evaluation

Shea, B., Reeves, B.C., Wells, G., Thuku, M., Hamel, C., Moran, J., et al. (2017). AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. BMJ, 358, j4008.

Validity

Shea, B. J., Reeves, B. C., Wells, G., Thuku, M., Hamel, C., Moran, J., et al. (2017). AMSTAR 2: A critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. BMJ (Clinical research ed.), 358, j4008. https://doi.org/10.1136/bmj.j4008

Reliability

Lorenz, R.C., Matthias, K., Pieper, D., Wegewitz, U., Morche, J., Nocon, M., et al. (2020). AMSTAR 2 overall confidence rating: Lacking discriminating capacity or requirement of high methodological quality? Journal of Clinical Epidemiology, 119, 142-144. https://doi.org/10.1016/j.jclinepi.2019.10.006.

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Registry