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Rapid Review: What are the risk factors for invasive meningococcal disease?

Several factors may be associated with increased risk of IMD, but findings are limited by low certainty evidence. Evidence for the risk of colonization by Neisseria meningitis is more robust, and points to age, sex, crowding and several behaviours associated with increased risk.


Citation:

Neil-Sztramko, S.E., Clark, E., Caldwell, S., Camargo, K., Leung, T., Dobbins, M. (2024, December 20). Rapid Review: What are the risk factors for invasive meningococcal disease? National Collaborating Centre for Methods and Tools’ Rapid Evidence Service. https://nccmt.ca/pdfs/res/imd

Public health topic area:

Public Health

Review question:
Population
Any (infants, children, adolescents, adults)
Comparisons
Absence of specific risk factors
Outcomes
Primary outcome: IMD caused by N. meningitidis, including meningococcal meningitis and meningococcal sepsis Secondary outcomes: N. meningitidis infection without IMD, e.g., conjunctivitis or urethritis; N. meningitidis carriage/colonisation of the nasopharynx N. meningitidis infection, for either primary or secondary outcomes, confirmed by PCR or antigen detection
Setting
Any location or setting (e.g., high-, middle-, and low-income countries)
Interest
Systematic reviews with or without meta-analysis, cohort studies, case-control studies, cross-sectional studies published between 2014 to 2024 about any risk factors (e.g., demographic characteristics, comorbidities, settings such as household crowing, closed or semi-closed communities, laboratories, etc.)
Search Updated:

Sep 10, 2024

Review Completed:

Dec 20, 2024